Botšepehi ke bothata bo ka sehloohong tlhahisong le ts'ebelisong ea sefaele.Lits'ebetsong tse ngata tsa mokelikeli (khase kapa mokelikeli), ho hlokahala botšepehi bo phahameng ba sefa nakong ea ho qetela ea tlhahiso le ka mor'a tšebeliso ea sebele.Ka hona, li-filters tsa lijo le lithethefatsi li tlameha ho ba le botšepehi bo tiileng ba liteko, litokomane tsa liteko le litlaleho
Integtest series integrity tester ke sesebediswa se ikgethang sa ho leka botshepehi ba disebediswa tsa sefa le disistimi tsa ho sefa, tse fihlelang ditlhoko tsa FDA, National Pharmacopoeia le GMP bakeng sa netefatso ya disefe tsa bactericidal.