Kev npaj yuav tsum tau "sib xyaw" cov khoom siv raw hauv qee qhov excipients los yog cov kuab tshuaj kom ncav cuag qhov xav tau concentration, thiab thaum kawg tuaj yeem muab rau lub hom phiaj siv tshuaj.Cov ntawv sib txawv ntawm kev npaj daws teeb meem ntawm kev siv tshuaj thiab ntau npaum li cas, tab sis kuj tseem muab cov kev xav tau siab dua rau kev nyab xeeb.Txhawm rau ua kom cov khoom sib xws thiab ruaj khov, cov khoom xyaw nquag ua tau raws li cov kev cai ntawm kev siv tshuaj, thiab tswj cov kev pheej hmoo, cov txheej txheem yuav tsum tau nruab nrog cov kev daws teeb meem kom paub meej cov khoom ua raws thiab kev nyab xeeb, raws li GMP cov cai.
Kev siv cov cuab yeej siv tshuaj niaj hnub no, cov tshuaj yuav raug cais tawm hauv cov qauv tshwj xeeb ntawm lub cev, txhawm rau hloov cov yam ntxwv pharmacokinetic thiab cov ntaub so ntswg faib cov tshuaj hauv lub cev, txhawm rau txhim kho cov txiaj ntsig ntawm cov nyhuv.Qhov no yuav tsum muaj cov lim dej aperture loj, muaj peev xwm cuam tshuam muaj zog, tsis muaj qhov to;Tsis muaj xov xwm tsiv teb tsaws, tsis cuam tshuam rau PH ntawm kev lag luam kws tshuaj;me me adsorption, ceev ceev ceev, tsis cuam tshuam cov ntsiab lus ntawm cov tshuaj tseem ceeb.