Pono ka ʻōnaehana lehulehu e hoʻolako i kahi kūlana paʻa a maʻemaʻe no ka hana ʻana.No ka wai, ke kinoea, ka ea i hoʻopili ʻia, ke kinoea inert, a me nā mea ʻē aʻe, pono ia e hoʻokō i nā koi maʻemaʻe o ke kaʻina hana lāʻau kūpono, GMP a me nā kuhikuhi a me nā lula.ʻO ka wai e pono ai i ka hana ʻana i ka ʻoihana lāʻau lapaʻau e mālama kūikawā ʻia.I mea e hōʻoiaʻiʻo ai i ka maʻemaʻe o ka hale hale hana a ʻaʻohe haumia i ke kaʻina fermentation, pono e hoʻomaʻemaʻe ʻia ke kinoea.
Hāʻawi ka ʻōnaehana lehulehu paʻa i ke kākoʻo ikaika no ka hana mau ʻana o nā ʻoihana.Pono nā ʻōnaehana wai, kinoea a me ka ea i ka hana ʻana i ka mālama kūikawā e hoʻokō i kā lākou mau hiʻohiʻona ponoʻī a me nā koi o ka GOOD manufacturing Practices a me nā alakaʻi a me nā lula pili.ʻO ka wai kaʻina hana: wai hoʻomaʻemaʻe, wai no ka injection, sterilization wai no ka injection, etc.